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In Vivo Research Scientist
Cybrexa is seeking a self-motivated, energetic and creative biologist with hands-on experience in rodent in vivo experimentation to take part in the development of novel therapeutics in oncology and report to the biology manager. Essential Job Functions and Duties As a Research Scientist, this position will provide in vivo support for the development and characterization …
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In Vivo Research Scientist
Cybrexa is seeking a self-motivated, energetic and creative biologist with hands-on experience in rodent in vivo experimentation to take part in the development of novel therapeutics in oncology and report to the biology manager.
Essential Job Functions and Duties
As a Research Scientist, this position will provide in vivo support for the development and characterization of small molecules. This will involve leading efficacy and PK/PD studies in mouse tumor models of cancer as well as catheterized rats. The Candidate should have extensive experience in performing pharmacology experiments to aid in the design of pre-clinical studies.
Knowledge, Skills and Abilities
- Experience handling and dosing rodents for PK/PD/efficacy experiments
- Experience developing, troubleshooting and validating in vivo assays
- Ability to multitask, document and organize studies in an electronic notebook, and effectively communicate experimental results at meetings
- Ability to collaborate with a multidisciplinary team of scientists
Education/Experience
The candidate should have a BS/MS degree with 5+ years of industry experience in biological sciences, with demonstrated scientific excellence. Previous experience in working drug discovery programs to develop compounds from the pre-clinical to the clinical setting would be preferred but not required.
Full or Part Time Animal Husbandry Position
Cybrexa is seeking an independent and self-motivated full time or part time lab technician to assist in mouse and rat animal husbandry and general lab maintenance. Essential Job Functions and Duties As a Lab Technician, this position will provide routine care to a small rodent colony including feeding and watering, monitoring vivarium environmental conditions and …
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Full or Part Time Animal Husbandry Position
Cybrexa is seeking an independent and self-motivated full time or part time lab technician to assist in mouse and rat animal husbandry and general lab maintenance.
Essential Job Functions and Duties
As a Lab Technician, this position will provide routine care to a small rodent colony including feeding and watering, monitoring vivarium environmental conditions and maintaining general sanitization of the vivarium, observing daily appearances and behaviors of experimental animals, assisting with dosing and collection of blood and other tissues, performing rodent euthanasia services according to established standards and practices and performing other duties as assigned.
Education/Experience
The candidate should be capable of performing basic animal care and laboratory duties with guidance, and effective verbal and written communication capabilities.
Clinical Operations Position Profile
Responsibilities Operational responsibility for the execution of clinical studies Develops and executes clinical trial operational strategies that are in compliance with Good Clinical Practice (GCP) Manages all aspects of relationships with Clinical Research Organizations (CROs) Helps develop site qualification forms for site selection. Participates in site selection decisions. Negotiates contracts and budgets with vendors and …
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Clinical Operations Position Profile
Responsibilities
- Operational responsibility for the execution of clinical studies
- Develops and executes clinical trial operational strategies that are in compliance with Good Clinical Practice (GCP)
- Manages all aspects of relationships with Clinical Research Organizations (CROs)
- Helps develop site qualification forms for site selection. Participates in site selection decisions.
- Negotiates contracts and budgets with vendors and clinical sites
- Reviews clinical protocols for operational feasibility
- Contributes to and reviews study conduct documents such as pharmacy manuals, pharmacokinetics manuals and sample collection manuals
- Works with CRO to develop case report forms (CRFs) and database build
- Develops logistical strategies for the collection and shipment of PK and biomarker samples from clinical sites to vendors for analysis
- Develops informed consent forms (ICFs)
- Develops vendor oversight plans (including auditing of CRO and other vendors)
- Develops and utilizes appropriate metrics to assess site and CRO performance, compliance and costs
- Establishes performance targets for the CRO. Holds CRO accountable for meeting performance targets
- Drafting and/or reviewing clinical department SOPs
- Develops vendor and site corrective action plans as needed
- Ensures audit readiness of company
- Data review and data cleaning
- Review of clinical research associates (CRAs) site monitoring reports
Minimum Qualifications
- BA/BS degree preferably in nursing, pharmacy, or relevant field (biology, chemistry). Advance degree preferred.
- 5+ years clinical oncology department experience in clinical operations or clinical science
- Working knowledge of phase 1 and phase 2 oncology clinical study design
- Experience working in cross-functional teams
General Skill Required
- Communication, problem solving, leadership, etc…